PCL monofilament


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PCL monofilament

PCL Thread



PCL Thread Advantages

Composition

Composition of PCL thread


PCL

• Biodegrdable biocompatible polymer
• 2 years degradation in the body

Neocollagenesis

Strong NeoCollagenesis


PCL(Polycaprolactone)
• PCL individually possess an excellent and proven safety-biocompatibility profile. This is proven through decades of extensive documented evidence from scientific literature and test results. It has been used successfully in numerous CE-marked and FDA-approved commercial bioresorbable medical devices for several decades world-wide.
• After being injected in the body, PCL is encapsulated by collagen presents in the body, escapes from phagocytosis, and then induces neo-collagenesis.

▶ Neocollagenesis of PCL


• PCL thread is encapsulated by collagen presents in the body, escapes from phagocytosis, and then induces neo-collagenesis.

• 10%~30% of volume increase effect can be expected.


▶ Histology after 1 month of PCLVitaminC thread (rat)

- Neocollagenesis observed around the thread

PCL vs PDO thread


PCL VitaminC thread
PDO thread
Main Component
• Polycaprolactone
• Polydioxanone
Neocollagenesis
• Proven
• Not proved so far clinically
Efficacy Length
• Long (1~2years)
  (PCL is used as the main component of a long lasting filler, Ellanse)
• Short (6 months)
   (PDO is wholely degraded in the body within 6 months)
Safety
• Perfectly safe
  (PCL CE marked & FDA approved materials)
• Not proved so far
  (Repetitive PDO injections for facial use is not clinically proved)
Dye used in the thread
• None
• D&C Violet 2
  (Tattoo effect many occur)

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